European Journal of Organic Chemistry (2013) 228-255

2,1,3-Benzothiadiazole and Derivatives: Synthesis, Properties, Reactions and Applications in Light Technology of Small Molecules

B. A. D. Neto*, A. A. M. Lapis, E. N. da Silva Júnior and J. Dupont

European Journal of Medicinal Chemistry 62 (2013) 98-110

Cytotoxicity of lapachol, Beta-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells

S. N. Sunasee*, C. G. L. Veale, N. Shunmoogan-Gouden, O. Osoniyi, D. T. Hendricks, M. R. Caira, J. L. Mare, A. L. Edkins, A. V. Pinto, E. N. da Silva Júnior and M. T. D. Coleman

Journal of the Brazilian Chemical Society 24 (2013) 145-163

Potent Antileukemic action of Naphthoquinoidal compounds: Evidence for an Intrinsic Death Mechanism based on Oxidative Stress and Inhibition of DNA Repair

B. Coelho*, I. O. Cabral, F. A. Rodrigues, F. W. A. Barros, D. D. Rocha, H. I. F. Magalhães, D. J. Moura, J. Saffi, J. A. P. Henriques, T. S. C. Carvalho, M. O. Moraes, C. Pessoa, I. M. M. Melo and E. N. da Silva Júnior*

European Journal of Medicinal Chemistry 63 (2013) 523-530

Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel alfa- and nor-alfa-lapachone-based 1,2,3-triazoles by copper-catalyzed azide alkyne cycloaddition

T. T. Guimarães, M. C. F. R. Pinto, J. S. Lanza, M. N. Melo, R. Monte, I. M. M. Melo, E. B. T. Diogo, V. F. Ferreira, C. A. Camara, W. O. Valença, R. N. Oliveira, F. Frezard and E. N. da Silva Júnior*

Bioorganic & Medicinal Chemistry 21 (2013) 6337-6348

Synthesis and anti-Trypanosoma cruzi activity of Naphthoquinone-containing Triazoles: Electrochemical studies on the effects of the quinoidal moiety

E. B. T. Diogo, G. G. Dias, B. L. Rodrigues, T. T. Guimarães, W. O. Valença, C. A. Camara, R. N. de Oliveira, M. G. da Silva, V. F. Ferreira, Y. G. Paiva, M. O. F. Goulart, R. F. S. Menna-Barreto, S. L. de Castro and E. N. da Silva Júnior*

European Journal of Medicinal Chemistry 69 (2013) 678-700

Synthesis of quinoidal molecules: Strategies towards bioactive compounds with an emphasis on lapachones

S. L. de Castro, F. S. Emery and E. N. Da Silva Júnior*

Revista Virtual de Química 5 (2013) 1022-1047

Aspectos da Obra Científica de Antonio Ventura Pinto: Uma Vida Dedicada ao Estudo da Reatividade Química de Quinonas Naturais e Sintéticas

V. F. Ferreira*, K. C. G. Moura, M. C. F. R. Pinto and E. N. da Silva Júnior

Journal of the Brazilian Chemical Societ 23 (2012) 770-781

Selective and Efficient Mitochondria Staining with Designed 2,1,3-Benzothiadiazole Derivatives as Live Cell Fluorescence Imaging Probes

B. A. D. Neto*, J. R. Correa, P. H. P. R. Carvalho, D. C. B. D. Santos, B. C. Guido, C. C. Gatto, H. C. B. Oliveira, M. Fasciotti, M. N. Eberlin and E. N. da Silva Júnior

Bioorganic & Medicinal Chemistry 20 (2012) 6482-6488

1,3-Azoles from ortho-naphthoquinones: Synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis

K. C. G. Moura, P. F. Carneiro, M. C. F. R. Pinto, J. A. Silva, V. R. S. Malta, C. A. Simone, G. G. Dias, G. A. M. Jardim, J. Cantos, T. S. Coelho, P. E. A. Silva* and E. N. da Silva Júnior*

European Journal of Medicinal Chemistry 52 (2012) 304-312

On the Search for Potential anti-Trypanosoma cruzi Drugs: Synthesis and Biological Evaluation of 2-Hydroxy-3-methylamino and 1,2,3-Triazolic Naphthoquinoidal Compounds obtained by Click Chemistry Reactions

E. N. da Silva Júnior*, I. M. M. Melo, E. B. T. Diogo, V. A. Costa, W. O. Valença, C. A. Camara, R. N. Oliveira, A. S. Araújo, F. S. Emery, M. R. Santos, C. A. de Simone, R. F. S. Menna-Barreto and S. L. Castro

Acta Farmaceutica Bonaerense 31 (2012) 507-513

Antimicrobial evaluation of quinones and heterocyclic compounds against Mycobacterium marinum, Mycobacterium kansasii and Mycobacterium abscessus

J. B. Cantos, T. S. Coelho, P. F. Carneiro, K. C. G. Moura, M. C. F. R. Pinto, E. N. da Silva Júnior and P. A. Silva*

Parasitology 139 (2012) 26-36

A novel triazolic naphthofuranquinone induces autophagy in reservosomes and impairment of mitosis in Trypanosoma cruzi

M. C. Fernandes, E. N. da Silva Júnior, A. V. Pinto, S. L. Castro and R. F. S. Menna-Barreto*

Toxicology in Vitro 26 (2012) 585-594

Growth inhibitory effects of 3'-Nitro-3-Phenylamino nor-beta-lapachone against HL-60: a redox dependent mechanism

A. J. Araujo, A. A. Souza, E. N. da Silva Júnior, J. D. B. Marinho Filho, M. A. B. F. de Moura, D. D. Rocha, M. C. Vasconcellos, C. O. Costa, C. Pessoa, C. M. O. Moraes, V. F. Ferreira, F. C. de Abreu, A. V. Pinto, R. C. Montenegro and L. V. Costa-Lotufo*, M. O. F. Goulart*

European Journal of Medicinal Chemistry 46 (2011) 399-410

Synthesis and evaluation of quinonoid compounds against tumor cell lines

E. N. Da Silva Júnior*, B. C. Cavalcanti, T. T. Guimarães, M. C. F. R. Pinto, I. O. Cabral, C. Pessoa, L. V. Costa-Lotufo, M. O. Moraes, C. K. Z. Andrade, M. R. Santos, C. A. Simone, M. O. F. Goulart and A. V. Pinto

Tetrahedron Letters 52 (2011) 2415-2418

Synthesis and characterisation of a new polycyclic phenazine from 1,4-naphthoquinone

M. J. Silva, M. C. F. R. Pinto, C. A. Simone, J. G. Soares, J. R. M. Reys, J. D. Souza Filho, W. T. A. Harrison, C. E. M. Carvalho, M. O. F. Goulart, E. N. da Silva Júnior* and A. V. Pinto

Molecules 16 (2011) 10314-10323

Antimony(V) and Bismuth(V) Complexes of Lapachol: Synthesis, Crystal Structure and Cytotoxic Activity

L. G. de Oliveira, M. M. Silva, F. C. S. de Paula, E. C. Pereira-Maia, C. L. Donnici, C. A. de Simone, F. Frézard, E. N. da Silva Júnior and C. Demicheli

European Journal of Medicinal Chemistry 46 (2011) 4521-4529

Quinonoid and phenazine compounds: Synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis

P. F. Carneiro, M. C. F. R. Pinto, T. S. Coelho, B. C. Cavalcanti, C. Pessoa, C. A. Simone, I. K. C. Nunes, N. M. de Oliveira, R. G. Almeida, A. V. Pinto, K. C. G. Moura, P. A. Silva* and E. N. da Silva Júnior*

Current Microbiology 62 (2011) 684-689

Identification of Nor-beta-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain

​

A. L. Lourenço, P. A. Abreu, B. Leal, E. N. da Silva Júnior, A. V. Pinto, M. C. F. R. Pinto, A. M. T. Souza, J. S. Novais, M. B. Paiva, L. M. Cabral, C. R. Rodrigues, V. F. Ferreira and H. C. Castro*

Chemical Research in Toxicology 24 (2011) 1560-1574

Preclinical Genotoxicology of Nor-Beta-lapachone in Human Cultured Lymphocytes and Chinese Hamster Lung Fibroblasts

B. C. Cavalcanti*, F. W. A. Barros, I. O. Cabral, J. R. O. Ferreira, H. I. F. Magalhaes, H. V. Nobre Júnior, E. N. da Silva Júnior, F. C. de Abreu, C. O. Costa, M. O. F. Goulart, M. O. Moraes and C. Pessoa