2013
European Journal of Organic Chemistry (2013) 228-255
35
2,1,3-Benzothiadiazole and Derivatives: Synthesis, Properties, Reactions and Applications in Light Technology of Small Molecules
B. A. D. Neto*, A. A. M. Lapis, E. N. da Silva Júnior and J. Dupont

European Journal of Medicinal Chemistry 62 (2013) 98-110
34
Cytotoxicity of lapachol, Beta-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells
S. N. Sunasee*, C. G. L. Veale, N. Shunmoogan-Gouden, O. Osoniyi, D. T. Hendricks, M. R. Caira, J. L. Mare, A. L. Edkins, A. V. Pinto, E. N. da Silva Júnior and M. T. D. Coleman

Journal of the Brazilian Chemical Society 24 (2013) 145-163
33
Potent Antileukemic action of Naphthoquinoidal compounds: Evidence for an Intrinsic Death Mechanism based on Oxidative Stress and Inhibition of DNA Repair
B. Coelho*, I. O. Cabral, F. A. Rodrigues, F. W. A. Barros, D. D. Rocha, H. I. F. Magalhães, D. J. Moura, J. Saffi, J. A. P. Henriques, T. S. C. Carvalho, M. O. Moraes, C. Pessoa, I. M. M. Melo and E. N. da Silva Júnior*


Featured in Front Cover
European Journal of Medicinal Chemistry 63 (2013) 523-530
32
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel alfa- and nor-alfa-lapachone-based 1,2,3-triazoles by copper-catalyzed azide alkyne cycloaddition
T. T. Guimarães, M. C. F. R. Pinto, J. S. Lanza, M. N. Melo, R. Monte, I. M. M. Melo, E. B. T. Diogo, V. F. Ferreira, C. A. Camara, W. O. Valença, R. N. Oliveira, F. Frezard and E. N. da Silva Júnior*

Bioorganic & Medicinal Chemistry 21 (2013) 6337-6348
31
Synthesis and anti-Trypanosoma cruzi activity of Naphthoquinone-containing Triazoles: Electrochemical studies on the effects of the quinoidal moiety
E. B. T. Diogo, G. G. Dias, B. L. Rodrigues, T. T. Guimarães, W. O. Valença, C. A. Camara, R. N. de Oliveira, M. G. da Silva, V. F. Ferreira, Y. G. Paiva, M. O. F. Goulart, R. F. S. Menna-Barreto, S. L. de Castro and E. N. da Silva Júnior*

European Journal of Medicinal Chemistry 69 (2013) 678-700
30
Synthesis of quinoidal molecules: Strategies towards bioactive compounds with an emphasis on lapachones
S. L. de Castro, F. S. Emery and E. N. Da Silva Júnior*

Revista Virtual de Química 5 (2013) 1022-1047
29
Aspectos da Obra Científica de Antonio Ventura Pinto: Uma Vida Dedicada ao Estudo da Reatividade Química de Quinonas Naturais e Sintéticas
V. F. Ferreira*, K. C. G. Moura, M. C. F. R. Pinto and E. N. da Silva Júnior
2012
Journal of the Brazilian Chemical Societ 23 (2012) 770-781
28
Selective and Efficient Mitochondria Staining with Designed 2,1,3-Benzothiadiazole Derivatives as Live Cell Fluorescence Imaging Probes
B. A. D. Neto*, J. R. Correa, P. H. P. R. Carvalho, D. C. B. D. Santos, B. C. Guido, C. C. Gatto, H. C. B. Oliveira, M. Fasciotti, M. N. Eberlin and E. N. da Silva Júnior


Featured in Front Cover
Bioorganic & Medicinal Chemistry 20 (2012) 6482-6488
27
1,3-Azoles from ortho-naphthoquinones: Synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis
K. C. G. Moura, P. F. Carneiro, M. C. F. R. Pinto, J. A. Silva, V. R. S. Malta, C. A. Simone, G. G. Dias, G. A. M. Jardim, J. Cantos, T. S. Coelho, P. E. A. Silva* and E. N. da Silva Júnior*

European Journal of Medicinal Chemistry 52 (2012) 304-312
26
On the Search for Potential anti-Trypanosoma cruzi Drugs: Synthesis and Biological Evaluation of 2-Hydroxy-3-methylamino and 1,2,3-Triazolic Naphthoquinoidal Compounds obtained by Click Chemistry Reactions
E. N. da Silva Júnior*, I. M. M. Melo, E. B. T. Diogo, V. A. Costa, W. O. Valença, C. A. Camara, R. N. Oliveira, A. S. Araújo, F. S. Emery, M. R. Santos, C. A. de Simone, R. F. S. Menna-Barreto and S. L. Castro

Acta Farmaceutica Bonaerense 31 (2012) 507-513
25
Antimicrobial evaluation of quinones and heterocyclic compounds against Mycobacterium marinum, Mycobacterium kansasii and Mycobacterium abscessus
J. B. Cantos, T. S. Coelho, P. F. Carneiro, K. C. G. Moura, M. C. F. R. Pinto, E. N. da Silva Júnior and P. A. Silva*
Parasitology 139 (2012) 26-36
24
A novel triazolic naphthofuranquinone induces autophagy in reservosomes and impairment of mitosis in Trypanosoma cruzi
M. C. Fernandes, E. N. da Silva Júnior, A. V. Pinto, S. L. Castro and R. F. S. Menna-Barreto*
Toxicology in Vitro 26 (2012) 585-594
23
Growth inhibitory effects of 3'-Nitro-3-Phenylamino nor-beta-lapachone against HL-60: a redox dependent mechanism
A. J. Araujo, A. A. Souza, E. N. da Silva Júnior, J. D. B. Marinho Filho, M. A. B. F. de Moura, D. D. Rocha, M. C. Vasconcellos, C. O. Costa, C. Pessoa, C. M. O. Moraes, V. F. Ferreira, F. C. de Abreu, A. V. Pinto, R. C. Montenegro and L. V. Costa-Lotufo*, M. O. F. Goulart*
2011
European Journal of Medicinal Chemistry 46 (2011) 399-410
22
Synthesis and evaluation of quinonoid compounds against tumor cell lines
E. N. Da Silva Júnior*, B. C. Cavalcanti, T. T. Guimarães, M. C. F. R. Pinto, I. O. Cabral, C. Pessoa, L. V. Costa-Lotufo, M. O. Moraes, C. K. Z. Andrade, M. R. Santos, C. A. Simone, M. O. F. Goulart and A. V. Pinto

Tetrahedron Letters 52 (2011) 2415-2418
21
Synthesis and characterisation of a new polycyclic phenazine from 1,4-naphthoquinone
M. J. Silva, M. C. F. R. Pinto, C. A. Simone, J. G. Soares, J. R. M. Reys, J. D. Souza Filho, W. T. A. Harrison, C. E. M. Carvalho, M. O. F. Goulart, E. N. da Silva Júnior* and A. V. Pinto

Molecules 16 (2011) 10314-10323
20
Antimony(V) and Bismuth(V) Complexes of Lapachol: Synthesis, Crystal Structure and Cytotoxic Activity
L. G. de Oliveira, M. M. Silva, F. C. S. de Paula, E. C. Pereira-Maia, C. L. Donnici, C. A. de Simone, F. Frézard, E. N. da Silva Júnior and C. Demicheli

European Journal of Medicinal Chemistry 46 (2011) 4521-4529
19
Quinonoid and phenazine compounds: Synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis
P. F. Carneiro, M. C. F. R. Pinto, T. S. Coelho, B. C. Cavalcanti, C. Pessoa, C. A. Simone, I. K. C. Nunes, N. M. de Oliveira, R. G. Almeida, A. V. Pinto, K. C. G. Moura, P. A. Silva* and E. N. da Silva Júnior*

Current Microbiology 62 (2011) 684-689
18
Identification of Nor-beta-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain
A. L. Lourenço, P. A. Abreu, B. Leal, E. N. da Silva Júnior, A. V. Pinto, M. C. F. R. Pinto, A. M. T. Souza, J. S. Novais, M. B. Paiva, L. M. Cabral, C. R. Rodrigues, V. F. Ferreira and H. C. Castro*
Chemical Research in Toxicology 24 (2011) 1560-1574
17
Preclinical Genotoxicology of Nor-Beta-lapachone in Human Cultured Lymphocytes and Chinese Hamster Lung Fibroblasts
B. C. Cavalcanti*, F. W. A. Barros, I. O. Cabral, J. R. O. Ferreira, H. I. F. Magalhaes, H. V. Nobre Júnior, E. N. da Silva Júnior, F. C. de Abreu, C. O. Costa, M. O. F. Goulart, M. O. Moraes and C. Pessoa
