2019

New Journal of Chemistry 43 (2019) 13751-13763
92

Copper complexes and carbon nanotube-copper ferrite-catalyzed benzenoid A-ring selenation of quinones: An efficient method for the synthesis of trypanocidal agents

 

G. A. M. Jardim, I. A. O. Bozzi, W. X. C. Oliveira, C. Mesquita-Rodrigues, R. F. S. Menna-Barreto, R. A. Kumar, E. Gravel, E. Doris,* A. L. Braga and E. N. da Silva Júnior*

Catalysis Science & Technology 9 (2019) 2742-2748 
91

Carbon nanotube-ruthenium hybrid towards mild oxidation of sulfides to sulfones: Efficient synthesis of diverse sulfonyl compounds

 

R. G. Almeida, R. L. de Carvalho, M. P. Nunes, R. S. Gomes, L. F. Pedrosa, C. A. de Simone, E. Gopi, V. Geertsen, E. Gravel, E. Doris* and E. N. da Silva Júnior*

Featured in Cover.

Highlighted in Themed collection 2019 Catalysis Science & Technology HOT Articles.

European Journal of Medicinal Chemistry 179 (2019) 863-915
90

Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones

 

E. N. da Silva Júnior,* G. A. M. Jardim, C. Jacob, U. Dhawa, L. Ackermann and S. L. de Castro

Bioorganic & Medicinal Chemistry 27 (2019) 4143-4150
89

Design of hybrid molecules as antimycobacterial compounds: Synthesis of isoniazid-naphthoquinone derivatives and their activity against susceptible and
resistant strains of Mycobacterium tuberculosis

W. J. Reis, I. A. O. Bozzi, M. F. Ribeiro, P. C. B. Halicki, L. A. Ferreira, P. E. A. da Silva, D. F. Ramos,* C. A. de Simone, E. N. da Silva Júnior*

Bioorganic & Medicinal Chemistry 27 (2019) 3938-3946
88

Natural product-inspired profluorophores for imaging NQO1 activity in tumour
tissues

 

Z. M. Cheng, W. O. Valença, G. G. Dias, J. Scott, N. D. Barth, F. Moliner, G. B. P. Souza, R. J. Mellanby, M. Vendrell,* E. N. da Silva Júnior*

Featured in the special issue 'Chemical Immunology'

Tetrahedron 75 (2019) 3697-3712 
87

Beyond Copper-Catalyzed Azide-Alkyne 1,3-dipolar Cycloaddition: Synthesis and
mechanism insights

 

R. S. Gomes, G. A. M. Jardim, R. L. de Carvalho, M. H. Araujo and E. N. da Silva Júnior*

European Journal of Organic Chemistry (2019) 2344-2353 
86

Ruthenium(II)-Catalyzed C–H Alkenylation of Quinones: Diversity-Oriented Strategy for Trypanocidal Compounds

 

G. G. Dias, T. A. do Nascimento, A. K. A. de Almeida, A. C. S. Bombaça, R. F. S. Menna-Barreto, C. Jacob, S. Warratz, E. N. da Silva Júnior* and L. Ackermann*

Free Radical Biology & Medicine 130 (2019) 408-418
85

Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles.

 

A. C. S. Bombaça, P. G. Viana, A. C. C. Santos, T. L. Silva, A. B. M. Rodrigues, A. C. R. Guimarães, M. O. F. Goulart, E. N. da Silva Júnior, R. F. S. Menna-Barreto* 

Physical Chemistry Chemical Physics 21 (2019) 3814-3821
84

Dynamics of aggregated states resolved by gated
fluorescence in films of room temperature phosphorescent emitters.

 

P. L. dos Santos, O. J. Silveira, R. Huang, G. A. M. Jardim, M. J. S. Matos, E. N. da Silva Júnior, A. P. Monkman, F. B. Dias, L. A. Cury*

Journal of Fluorine Chemistry 220 (2019) 9-15
83

On the synthesis, optical and computational studies of novel BODIPY-based phosphoramidate fluorescent dyes.

 

L. A. Machado, M. C. de Souza, C. M. da Silva, J. Yoneda, L. C. D. de Rezende, F. S. Emery, C. A. de Simone, E. N. da Silva Júnior,* L. F. Pedrosa*

Physical Chemistry Chemical Physics 21 (2019) 21966-21971
82

Multi-conformational monomer and dimer steady-states in domains of few molecules: the consequences on the phosphorescence emission bands.

G. H. R. Soares, G. A. M. Jardim, E. N. da Silva Júnior, L. A. Cury*

2018

Chemical Society Reviews 47 (2018) 12-27
81

Quinone-based fluorophores for imaging biological processes

 

G. G. Dias, A. King, F. de Moliner, M. Vendrell* and E. N. da Silva Júnior*

Featured in Front Cover

Highlighted in Themed collection 2018 Emerging Investigators.

Highlighted in Themed collection SBQ-RSC: Celebrating UK-Brazil collaborations.

Chemical Science 9 (2018) 6899-6903
80

Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor

 

T. Rodrigues*, M. Werner, J. Roth, E. H. G. da Cruz, M. C. Marques, P. Akkapeddi, S. A. Lobo, A. Koeberle, F. Corzana, E. N. da Silva Júnior, O. Werz, G. J. L. Bernardes*

Chemical Communications 54 (2018) 7398-7411
79

Weakly-coordinating N-oxide and carbonyl groups for metal catalyzed C–H activation: The case of A-ring functionalization

 

E. N. da Silva Júnior*, G. A. M. Jardim, R. S. Gomes, Y.-F. Liang and L. Ackermann*

Featured in Inside Front Cover.

Chemistry A European Journal 24 (2018) 15227-15235
78

Combination of Aryl Diselenides/Hydrogen Peroxide and Carbon Nanotube-Rhodium Nanohybrid for Naphthols Oxidation: An Efficient Route towards Trypanocidal Quinones

 

R. L. de Carvalho, G. A. M. Jardim, A. C. C. Santos, M. H. Araujo, W. X. C. Oliveira, A. C. S. Bombaça, R. F. S. Menna-Barreto, E. Gopi, E, Gravel, E. Doris*, E. N. da Silva Júnior*

Featured in Front Cover and Selected as HOT PAPER.

Chemical Communications 54 (2018) 12840-12843
77

Ruthenium-catalyzed C–H oxygenation of quinones by weak O-coordination for potent trypanocidal agents

 

G. G. Dias, T. Rogge, R. Kuniyil, C. Jacob, R. F. S. Menna-Barreto, E. N. da Silva Júnior* and L. Ackermann*

European Journal of Medicinal Chemistry 151 (2018) 686-704
76

Quinonoid Compounds via Reactions of Lawsone and 2-Aminonaphthoquinone with α-Bromonitroalkenes and Nitroallylic Acetates: Structural Diversity by C-ring Modification and Cytotoxic Evaluation against Cancer Cells

 

T. V. Baiju, R. G. Almeida, S. T. Sivanandan, C. A. de Simone, L. M. Brito, B. C. Cavalcanti, C. Pessoa, I. N. N. Namboothiri* and E. N. da Silva Júnior*

Organic & Biomolecular Chemistry 16 (2018) 1686-1691
75

Direct sequential C-H iodination/organoyl-thiolation for benzenoid A-ring modification of quinonoid deactivated systems: A new protocol for potent trypanocidal quinones

 

G. A. M. Jardim, W. X. C. Oliveira, R. P. de Freitas, R. F. S. Menna-Barreto, T. L. Silva, M. O. F. Goulart and E. N. da Silva Júnior*

Molecules 23 (2018) 83
74

Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions

 

G. A. M. Jardim, E. H. G. da Cruz, W. O. Valença, D. J. B. Lima, B. C. Cavalcanti, C. Pessoa, J. Rafique, A. L. Braga, C. Jacob* and E. N. da Silva Júnior*

Chemical Physics Letters 695 (2018) 176-182
73

Vibronic singlet and triplet steady-state interplay emissions in phenazine-based 1,2,3-triazole films

 

B. B. A. Costa, P. D. C. Souza, R. N. Gontijo, G. A. M. Jardim, R. L. Moreira, E. N. da Silva Júnior, L. A. Cury*

Journal of Fluorine Chemistry 205 (2018) 8-14
72

Multinuclear NMR spectroscopy, photophysical, electrochemical and DNA-binding properties of fluorinated 1,8-naphthyridine-based boron heterocycles

 

H. G. Bonacorso*, T. P. Calheiro, B. A. Iglesias, Carolina H. da Silveira, E. N. da Silva Júnior, A. Ketzer, F. Bublitz, N. Zanatta, M. A. P. Martins

Current Topics in Medicinal Chemistry 18 (2018) 1-7
71

A UBI 31-38 Peptide-coumarin Conjugate: Photophysical Features, Imaging Tracking and Synergism with Amphotericin B Against Cryptococcus

 

S. M. Z. M. D. Ferreira, H. C. Carneiro, R. B. Alves, A. C. S. Batista, E. N. da Silva Júnior, G. G. Dias, J. M. Resende, D. A. Santos, D. L. Oliveira, M. L. Rodrigues, R. P. Freitas*

Frontiers in Chemistry 6 (2018) 339
70

Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplet

F. de Moliner, A. King, G. G. Dias, G. F. de Lima, C A. de Simone, E N. da Silva Júnior,* M. Vendrell*

Microbial Pathogenesis 117 (2018) 32-42
69

Action mechanism of naphthofuranquinones against fluconazole-resistant Candida tropicalis strains evidenced by proteomic analysis: The role of increased endogenous ROS

J. B. A. Neto, C. R. da Silva, R. S. Campos, F. B. S. A. do Nascimento, L. S. Sampaio, A. R. da Silva, M. A. A. Josino, M. O. de Moraes, M. D. P. Lobo, F. B. M. B. Moreno, A. C. O. M. Moreira, R. A. Moreira, T. B. Grangeiro, E. N. da Silva Júnior, H. I. F. Magalhães, D. D. Rocha, B. C. Cavalcanti, H. V. Nobre Júnior*

2017

Physical Chemistry Chemical Physics 19 (2017) 3473-3479
68

Indirect consequences of exciplex states on the phosphorescence lifetime of phenazine-based 1,2,3-triazole luminescent probe

 

B. B. A. Costa, G. A. M. Jardim, P. L. Santos, H. D. R. Calado, A. P. Monkman, F. B. Dias, E. N. da Silva Júnior, L. A. Cury*

Featured in Front Cover.

Highlighted in Themed collection SBQ-RSC: Celebrating UK-Brazil collaborations.

European Journal of Medicinal Chemistry 136 (2017) 406-419
67

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones

 

G. A. M. Jardim, T. L. Silva, M. O. F. Goulart, C. A. de Simone, J. M. C. Barbosa, K. Salomão, S. L. de Castro, J. F. Bower and E. N. da Silva Júnior*

ChemistrySelect 2 (2017) 4301-4308
66

Synthesis of Quinone-Based N-Sulfonyl-1,2,3-triazoles: Chemical Reactivity of Rh(II) Azavinyl Carbenes and Antitumor Activity

 

W. O. Valença, T. V. Baiju, F. G. Brito, M. H. Araujo, C. Pessoa, B. C. Cavalcanti, C. A. de Simone, C. Jacob, I. N. N. Namboothiri* and E. N. da Silva Júnior*

New Journal of Chemistry 41 (2017) 3723-3731
65

Cyclometalated ruthenium complexes from naturally occurring quinones: Studies on their photophysical features, computational details and trypanocidal activity

 

C. M. de Souza, R. C. Silva, P. O. Fernandes, J. D. de Souza Filho, H. A. Duarte, M. H. Araujo, C. A. de Simone, S. L. de Castro, R. F. S. Menna-Barreto, C. P. Demicheli and E. N. da Silva Júnior*

Featured in Front Cover.

European Journal of Organic Chemistry (2017) 3763-3773
64

Redox Center Modification of Lapachones Toward the Syntheses of Nitrogenated Heterocycles as Selective Fluorescent Mitochondrial Imaging Probes

 

F. S. dos Santos, G. G. Dias, R. P. de Freitas, Lucas S. Santos, G. F. de Lima, H. A. Duarte, C. A. de Simone, L. M. S. L. Rezende, M. J. X. Vianna, J. R. Correa, B. A. D. Neto and E. N. da Silva Júnior*

Featured in Front Cover.

Bioorganic & Medicinal Chemistry Letters 27 (2017) 4446-4456
63

On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells

 

T. B. Gontijo, R. P. de Freitas, F. S. Emery, L. F. Pedrosa, J. B. Vieira Neto, B. C. Cavalcanti, C. Pessoa, A. King, F. de Moliner, M. Vendrell and E. N. da Silva Júnior*

Medicinal Chemical Communications 8 (2017) 1993-2002
62

Encapsulation of nor-β-lapachone into poly(D,L)-lactide-co-glycolide (PLGA) microcapsules: full characterization, computational details and cytotoxic activity against human cancer cell lines

 

M. P. Costa, A. C. S. Feitosa, F. C. E. Oliveira, B. C. Cavalcanti, G. G. Dias, E. W. S. Caetano, F. A. M. Sales, V. N. Freire, S. Di Fiore, R. Fischer, L. O. Ladeira, E. N. da Silva Júnior* and C. Pessoa*

Laboratory of Synthetic and Heterocyclic Chemistry,

Institute of Exact Sciences, Department of Chemistry,
Federal University of Minas Gerais, Belo Horizonte, Brazil

Adress : Av. Pres. Antônio Carlos, 6627 - Pampulha,

Belo Horizonte - MG

E-mail: eufranio@ufmg.br

Phone Number: +55 31 34095696