da Silva Júnior Group
Organic and Medicinal chemistry
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2024
The Synthesis and Reactivity of Naphthoquinonynes
R. L. de Carvalho, J. M. Wood, R. G. Almeida, N. G. Berry, E. N. da Silva Júnior* and J. F. Bower*
Bypassing Ammonia: From N2 to Nitrogen Heterocycles without N1 Intermediates or Transition Metals
M. Weber, T. Kupfer, M. Arrowsmith, R. D. Dewhurst, M. Rang, B. Ritschel, S. Titlbach, M. Ernst, M. Oliveira Rodrigues, E. N. da Silva Júnior and H. Braunschweig*
Electrochemical Diselenation of BODIPY Fluorophores for Bioimaging Applications and Sensitization of singlet oxygen
Í. A. O. Bozzi, L. A. Machado, E. B. T. Diogo, F. G. Delolo, L. O. F. Barros, G. A. P. Graça, M. H. Araujo, F. T. Martins, L. F. Pedrosa, L. C. da Luz, E. S. Moraes, F. S. Rodembusch, J. S. F. Guimarães, A. G. Oliveira, S. H. Röttger, D. B. Werz, C. P. Souza, F. Fantuzzi, J. Han, T. B. Marder, H. Braunschweig* and E. N. da Silva Júnior*
This article also appears in: Hot Topic: Fluorine Chemistry Society Volumes: Germany
Featured in Front Cover
Cover Profile: Electrochemical Diselenation of BODIPY Fluorophores for Bioimaging Applications and Sensitization of singlet oxygen
Í. A. O. Bozzi, L. A. Machado, E. B. T. Diogo, F. G. Delolo, L. O. F. Barros, G. A. P. Graça, M. H. Araujo, F. T. Martins, L. F. Pedrosa, L. C. da Luz, E. S. Moraes, F. S. Rodembusch, J. S. F. Guimarães, A. G. Oliveira, S. H. Röttger, D. B. Werz, C. P. Souza, F. Fantuzzi, J. Han, T. B. Marder, H. Braunschweig* and E. N. da Silva Júnior*
Waveguided phosphorescence through a gain medium by an in-plane pulsed laser stripe
W. J. E. de Paula, G. A. M. Sáfar, E. N. da Silva Júnior and L. A. Cury*
BODIPYs as Fluorogenic Probes for Live-Cell Imaging of Lipid Droplets: Photophysical and Computational Studies
L. A. Machado, C. L. M. Pereira, A. C. G. de Souza, E. A. Ferreira, F. F. C. Marques, E. Orestes, M. H. Araujo, K. L. R. Paiva, M. S. Mesquita, S. N. Báo,* L. F. Pedrosa, M. J. Nasim, C. Jacob* and E. N. da Silva Júnior*
2023
The Crucial Role of Silver(I)-Salts as Additives on C–H Activation Reactions: Overall Analysis of their Versatility and Applicability
R. L. de Carvalho, E. B. T. Diogo, S. L. Homölle, S. Dana, E. N. da Silva Júnior* and L. Ackermann*
This article is part of the themed collections: 2023 Pioneering Investigators and Celebrating the scientific accomplishments of RSC Fellows
Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity
R. Alhasan, G. M. Martins, P. P. de Castro, R. S. Z. Saleem, A. Zaiter, I. Fries-Raeth, A. Kleinclauss, C. Perrin-Sarrado, P. Chaimbault, E. N. da Silva Júnior*, C. Gaucher* and C. Jacob
Electrochemical Sulphenylation/Cyclization of Quinones: A Rapid, Green and Efficient Access to Cytotoxic Compounds
E. B. T. Diogo, F. G. Delolo, G. A. P. Graça, E. R. S. Paz, I. A. O. Bozzi, R. Diniz, J. P. Passos, T. Matencio, L. K. Soares, D. Alves, P. M. S. Costa, C. Pessoa, C. L. M. Pereira, L. Ackermann* and E. N. da Silva Júnior*
Solvent-free hydroboration of alkenes and alkynes catalyzed by rhodium-ruthenium nanoparticles on carbon nanotubes
M. P. Nunes, D. V. Jawale, F. G. Delolo, M. H. Araujo, E. Gravel,* E. Doris* and E. N. da Silva Júnior*
Featured in Synfacts 2023, 19, 0601.
It Takes Two to Tango, Part II: Synthesis of A-ring Functionalised Quinones Containing Two Redox-Active Centres with Antitumour Activities
J. C. de Oliveira, R. L. de Carvalho, H. G. S. Sampaio, J. Honorato, J. A. Ellena, F. T. Martins, J. V. M. Pereira, P. M. S. Costa, C. Pessoa, R. S. Ferreira, M. H. Araújo, C. Jacob and E. N. da Silva Júnior*
​ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics
R. J. Oliveira,* I. O. M. F. Silveira, S. C. Neves, B. Mitsuyasu, A. C. Martins, C. Berno, J. Mohammad, H. Raj, F. H. S. de Araujo, C. R. Hortelan, L. Machado, E. N. da Silva Júnior, M. L. B. Vilela, V. A. Nascimento, A. Beatriz and R. S. Gomes*
Featured in Front Cover
Sensitive Hydrazine Detection and Quantification with a Fluorescent Benzothiadiazole Sensor: Selective Lipid Droplets and In Vivo Imaging
C. O. Santos, S. T. A. Passos, J. E. P. Sorto, D. F. S. Machado, J. R. Correia, E. N. da Silva Júnior, M. O. Rodrigues and B. A. D. Neto*
Featured in Front Cover
First report of trans-A2B-corrole derived from a lapachone derivative: Photophysical, TD-DFT and Photobiological assays
B. M. Rodrigues, C. C. Diniz, V. N. da Rocha, M. H. Köhler, G. P. Brandão, L. A. Machado, E. N. da Silva Júnior* and B. A. Iglesias*
From the themed collection: Emerging Investigators Series
Imidazole-based optical sensors as a platform for bisulfite sensing and BSA/HSA interaction study. An experimental and theoretical investigation
E. R. S. Paz, V. G. Isoppo, F. S. dos Santos, L. A. Machado, R. P. de Freitas, H. C. Silva Junior, O. A. Chaves, B. A. Iglesias, F. S. Rodembusch* and E. N. da Silva Júnior*
2022
Aryl-phenanthro[9,10-d]imidazole: A versatile scaffold for the design of optical-based sensors
G. G. Dias, M. O. Rodrigues, E. R. S. Paz, M. P. Nunes, M. H. Araujo, F S. Rodembusch* and E. N. da Silva Júnior*
Looking deep into C–H functionalization: the synthesis and application of cyclopentadienyl and related metal catalyst
G. A. M. Jardim, R. L. de Carvalho, M. P. Nunes, L. A. Machado, L. D. Almeida, K. A. Bahou, J. F. Bower* and E. N. da Silva Júnior*
Ruthenium(II)-Catalyzed C–H/N–H Alkyne Annulation of Nonsymmetric Imidazoles: Mechanistic Insights by Computation and Photophysical Properties
L. A. Machado, E. R. S. Paz, M. H. Araujo, L. D. Almeida, I. A. O. Bozzi, G. G. Dias, C. L. M. Pereira, L. F. Pedrosa, F. Fantuzzi, F. T. Martins, L. A. Cury and E. N. da Silva Júnior*
Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2
A. J. O'Donoghue,* E. N. da Silva Júnior,* R. S. Ferreira* and co-workers
Lanthanide(III)-oxamato complexes containing Nd(III) and Ho(III): crystal structures, magnetic properties, and ab initio calculations
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R. C. A. Vaz, I. O. Esteves, W. X. C. Oliveira, J. Honorato, F. T. Martins, E. N. da Silva Júnior, D. C. A. Valente, T. M. Cardozo, B. A. C. Horta, D. L. Mariano, W. C. Nunes, E. F. Pedroso and C. L. M. Pereira*
Featured in Front Cover
X-ray structure and magnetic properties of a mononuclear complex and a 1D coordination polymer assembled by cobalt(II) ions and a flexible oxamate ligand
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J. Parreiras, E. N. Faria, W. X. C. Oliveira, C. B. Pinheiro, W. D. do Pim, E. N. da Silva Júnior, E. F. Pedroso, M. Julve and C. L. M. Pereira*
Design, Synthesis and in vivo Evaluation of 1,4-dioxo-2-butenyl Aryl Amine Derivatives as a Promising Anti-inflammatory Drug Prototype
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I. O. M. F. da Silveira, I. S. B. Moslaves, J. A. I. Muller, R. J. Oliveira, C. R. W. Hortelan, T. T. Okuyama, J. Fernandes, B. Badenoch, L. J. de Campos, L. D. Almeida, J. Mohammad, A. C. F. Martins, A. Beatriz, E. N. da Silva Júnior, M. C. Toffoli-Kadri* and R. S. Gomes*
Multi-conformational luminescence and phosphorescence of few phenazine 1,2,3-triazole molecules
P. B. Pinto, K. C. T. da Cruz, E. N. da Silva Júnior and L. A. Cury*
Rational Design and Synthesis of Large Stokes Shift 2,6-Sulphur-Disubstituted BODIPYs for Cell Imaging
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A. E. Reese, C. Lochenie, A. Geddis, L. A. Machado, M. C. de Souza, F. F. C. Marques, C. A. de Simone, M. M. Gouvêa, L. F. Pedrosa, E. N. da Silva Júnior* and Marc Vendrell*
This article belongs to the Special Issue Selected Papers from Optical Materials: Synthesis and Biological Applications Symposium (XXXVIII Biennial Meeting RSEQ)
Raman spectra-based structural classificatory analysis of quinoidal and derivative molecular systems
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A. P. Pena, R. G. Almeida, J. Campos, H. F. dos Santos, E. N. da Silva Júnior and A. Jorio*
2021
Introduction to celebrating Latin American talent in chemistry
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G. Merino,* M. A. Fernandez-Herrera,* G. J. A. A. Soler-Illia, A. J. G. Zarbin,* V. G. Zuin, E. Chamorro,* L. G. de Oliveira, M. F. Mesko, C. Fraga, I. A. I. Alvarado, J. Dupont, A. F. Nogueira, C. F. O. Graeff, H. O. Pastore, E. N. da Silva Júnior and O. Azzaroni
This article is part of the themed collection: Celebrating Latin American Talent in Chemistry
Special issue: The Brazilian Meeting on Organic Synthesis
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A. Fatima and E. N. da Silva Júnior*
Featured in Front Cover
On the application of 3d metals for C–H activation toward bioactive compounds:
The key step for the synthesis of silver bullets
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R. L. Carvalho, A. S. de Miranda, M. P. Nunes, R. S. Gomes, G. A. M. Jardim* and E. N. da Silva Júnior*
Decoding directing groups and their pivotal role in C–H activation
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K. Murali, L. A. Machado, R. L. Carvalho, L. F. Pedrosa, R. Mukherjee, E. N. da Silva Júnior* and D. Maiti*
A Catalysis Guide Focusing on C–H Activation Processes
R. L. Carvalho, G. G. Dias, C. L. M. Pereira, P. Ghosh, D. Maiti* and E. N. da Silva Júnior*
Featured in Front Cover
Removal and modification of directing groups used in metal-catalyzed C–H functionalization: The magical step of conversion into ‘conventional’ functional groups
R. L. Carvalho, R. G. Almeida, M. Karunanidhi, L. A. Machado, L. F. Pedrosa, P. Dolui, D. Maiti* and E. N. da Silva Júnior*
Transition-Metal-Catalyzed Selective Alkynylation of C-H Bonds
A. S. Sarala, S. Bhowmick, R. L. de Carvalho, S. A. Al-Thabaiti, M. Mokhtar, E. N. da Silva Júnior* and D. Maiti*
Rhodium(III)-Catalyzed C–H/N–H Alkyne Annulation of nonsymmetric 2-aryl (benz)imidazole derivatives:
Photophysical and Mechanistic Insights
G. G. Dias, E. R. S. Paz, J. Y. Kadooca, A. A. Sabino, L. A. Cury, K. Torikai, C. A. de Simone, F. Fantuzzi and E. N. da Silva Júnior*
It takes two to Tango: Synthesis of cytotoxic quinones containing two redox active centers with potential antitumor activity
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D. J. B. Lima, R. G. Almeida, G. A. M. Jardim, B. P. A. Barbosa, A. C. C. Santos, W. O. Valença, M. R. Scheide, C. C. Gatto, G. G. C. de Carvalho, P. M. S. Costa, C. Pessoa, C. L. M. Pereira, C. Jacob, A. L. Braga* and E. N. da Silva Júnior*
Liposomes containing 3-arylamino-nor-β-lapachone derivative: development, characterization, and in vitro evaluation of the cytotoxic activity
L. V. Rebouças, F. C. E. Oliveira, D. P. Pinheiro, A. C. A. Oliveira, R. G. Almeida, E. N. da Silva Júnior, M. S. Rizzo, M. P. Costa*, G. Zocolo, F. O. S. Ribeiro, D. A. da Silva and C. Pessoa
The Different Facets of Metal-Catalyzed C–H Functionalization Involving Quinone Compounds
J. M. Wood, R. L. Carvalho and E. N. da Silva Júnior*
This article also appears in: 18th Brazilian Meeting on Organic Synthesis and Hot Topic: C-H Activation
Ruthenium(II)- and Palladium(II)-Catalyzed Position-Divergent C–H
Oxygenations of Arylated Quinones: Identification of Hydroxylated Quinonoid
Compounds with Potent Trypanocidal Activity
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T. B. Gontijo, R. L. Carvalho, L. Dantas-Pereira, R. F. S. Menna-Barreto, T. Rogge, L. Ackermann* and E. N. da Silva Júnior*
Imidazoles and Oxazoles from Lapachones and Phenanthrene-9,10-dione: A Journey through their Synthesis, Biological Studies, and Optical Applications
G. G. Dias, E. R. S. Paz, M. P. Nunes, R. L. Carvalho, M. O. Rodrigues, F. S. Rodembusch* and E. N. da Silva Júnior*
Synthesis of β-triazolylenones via metal-free desulfonylative alkylation of N-tosyl-1,2,3-triazoles
S. Pati, R. G. Almeida, E. N. da Silva Júnior* and I. N. N. Namboothiri*
Benzo[a]phenazine derivatives: promising scaffolds to combat resistant Mycobacterium tuberculosis
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P. C. B. Halicki, E. N. da Silva Júnior, G. A. M. Jardim, R. G. de Almeida, J. R. M. Vicenti, B. L. Gonçalves, P. E. Almeida da Silva and D. F. Ramos*
Cathepsin K inhibitors based on 2-amino-1,3,4-oxadiazole derivatives
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T. B. Gontijo, P. S. Lima, M. Y. Icimoto, E. C. de Alvarenga, A. K. Carmona, A. A. de Castro, T. C. Ramalho, E. N. da Silva Júnior and R. P. de Freitas*
Ferromagnetic coupling in a dicopper(II) oxamate complex bridged by carboxylate groups
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T. T. da Cunha, C. O. C. da Silveira, V. M. M. Barbosa, W. X. C. Oliveira, E. N. da Silva Júnior, F. F. Ferreira, E. F. Pedroso, C. L. M. Pereira*
Featured in Front Cover
From the themed collection: Supramolecular & Polymorphism
Unexpected formation of a dodecanuclear {CoII6CuII6} nanowheel under ambient conditions: magneto-structural correlations
W. D. do Pim, I. F. Silva, E. N. da Silva Júnior, H. O. Stumpf, W. X. C. Oliveira, E. F. Pedroso, C. B. Pinheiro, Y. Journaux, F. Fantuzzi, I. Krummenacher, H. Braunschweig, B. Engels, J. Cano, M. Julve and C. L. M. Pereira*
Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities
L. Dantas-Pereira, E. F. Cunha-Júnior, V. V. Andrade-Neto, J. F. Bower, G. A. M. Jardim, E. N. da Silva Júnior, E. C. Torres-Santos and R. F. S. Menna-Barreto*
2020
Rh-catalyzed [2+2+2] cycloadditions with benzoquinones: de novo access to naphthoquinones for lignan and type II polyketide synthesis
J. M. Wood, E. N. da Silva Júnior* and J. F. Bower*
Part of a Special Issue: Celebrating Chemistry in Latin America
Ruthenium(II)-Catalyzed Double Annulation of Quinones: Step-Economical Access to Valuable Bioactive Compounds
E. N. da Silva Júnior,* R. L. de Carvalho, R. G. Almeida, L. G. Rosa, F. Fantuzzi, T. Rogge, P. M. S. Costa, C. Pessoa, C. Jacob and L. Ackermann*
Part of a Special Issue for the 8th EuChemS Chemistry Congress consisting of contributions from selected speakers and conveners.
To view the complete issue, visit Issue 48.
Synthesis of Densely Substituted Sulfonylfurans and Dihydrofurans via Cascade Reactions of α-Functionalized Nitroalkenes with β-Ketosulfones
V. Mane, S. Sivanandan, R. Santana, A. Beatriz, E. N. da Silva Júnior* and I. N. N. Namboothiri*
Featured in Front Cover
Electrochemical selenation/cyclization of quinones: A rapid, green and efficient access to functionalized trypanocidal and
antitumor compounds
A. Kharma, C. Jacob,* I. A. O. Bozzi, G. A. M. Jardim, A. L. Braga, K. Salomão, C. C. Gatto, M. F. S. Silva, C. Pessoa, M. Stangier, L. Ackermann* and E. N. da Silva Júnior*
Featured in Front Cover
Strategies towards potent trypanocidal drugs: application of Rh-catalyzed [2+2+2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi
J. M. Wood, N. S. Satam, R. G. Almeida, V. S. Cristani, D. P. Lima, L. D. Pereira, K. Salomão, R. F. S. Menna-Barreto, I. N. N. Namboothiri*, J. F. Bower* and E. N. da Silva Júnior*
Synthesis of quinone imine and sulphur-containing compounds with antitumor and trypanocidal activities: Redox and biological implications
R. G. Almeida, W. O. Valença, L. G. Rosa, C. A. de Simone, S. L. de Castro, J. M. C. Barbosa, D. P. Pinheiro, C. R. K. Paier, G. G.
C. de Carvalho, C. Pessoa, M. O. F. Goulart, A. Kharma and E. N. da Silva Júnior*
Featured in Front Cover
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C. R. da Silva,* R. de S Campos, J. B. A. Neto, L. S. Sampaio, F. B. S. A. do Nascimento, L. G. A. V. Sá, T. M. Cândido, H. I. F. Magalhães, E. H. G. da Cruz, E. N. da Silva Júnior, M. O. de Moraes, B. C. Cavalcanti, J. Silva, E. S Marinho and H. V. N. Júnior*
2019
Copper complexes and carbon nanotube-copper ferrite-catalyzed benzenoid A-ring selenation of quinones: An efficient method for the synthesis of trypanocidal agents
G. A. M. Jardim, I. A. O. Bozzi, W. X. C. Oliveira, C. Mesquita-Rodrigues, R. F. S. Menna-Barreto, R. A. Kumar, E. Gravel, E. Doris,* A. L. Braga and E. N. da Silva Júnior*
Highlighted in Themed collection Selenium & Tellurium chemistry at the beginning of the 3rd millennium: a celebration of ICCST, 2019.
Carbon nanotube-ruthenium hybrid towards mild oxidation of sulfides to sulfones: Efficient synthesis of diverse sulfonyl compounds
R. G. Almeida, R. L. de Carvalho, M. P. Nunes, R. S. Gomes, L. F. Pedrosa, C. A. de Simone, E. Gopi, V. Geertsen, E. Gravel, E. Doris* and E. N. da Silva Júnior*
Featured in Cover.
Highlighted in Themed collection 2019 Catalysis Science & Technology HOT Articles.
Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones
E. N. da Silva Júnior,* G. A. M. Jardim, C. Jacob, U. Dhawa, L. Ackermann and S. L. de Castro
Design of hybrid molecules as antimycobacterial compounds: Synthesis of isoniazid-naphthoquinone derivatives and their activity against susceptible and
resistant strains of Mycobacterium tuberculosis
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W. J. Reis, I. A. O. Bozzi, M. F. Ribeiro, P. C. B. Halicki, L. A. Ferreira, P. E. A. da Silva, D. F. Ramos,* C. A. de Simone and E. N. da Silva Júnior*
Natural product-inspired profluorophores for imaging NQO1 activity in tumour
tissues
Z. M. Cheng, W. O. Valença, G. G. Dias, J. Scott, N. D. Barth, F. Moliner, G. B. P. Souza, R. J. Mellanby, M. Vendrell* and E. N. da Silva Júnior*
Featured in the special issue 'Chemical Immunology'
Beyond Copper-Catalyzed Azide-Alkyne 1,3-dipolar Cycloaddition: Synthesis and
mechanism insights
R. S. Gomes, G. A. M. Jardim, R. L. de Carvalho, M. H. Araujo and E. N. da Silva Júnior*
Ruthenium(II)-Catalyzed C–H Alkenylation of Quinones: Diversity-Oriented Strategy for Trypanocidal Compounds
G. G. Dias, T. A. do Nascimento, A. K. A. de Almeida, A. C. S. Bombaça, R. F. S. Menna-Barreto, C. Jacob, S. Warratz, E. N. da Silva Júnior* and L. Ackermann*
Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles.
A. C. S. Bombaça, P. G. Viana, A. C. C. Santos, T. L. Silva, A. B. M. Rodrigues, A. C. R. Guimarães, M. O. F. Goulart, E. N. da Silva Júnior and R. F. S. Menna-Barreto*
Dynamics of aggregated states resolved by gated
fluorescence in films of room temperature phosphorescent emitters.
P. L. dos Santos, O. J. Silveira, R. Huang, G. A. M. Jardim, M. J. S. Matos, E. N. da Silva Júnior, A. P. Monkman, F. B. Dias and L. A. Cury*
On the synthesis, optical and computational studies of novel BODIPY-based phosphoramidate fluorescent dyes.
L. A. Machado, M. C. de Souza, C. M. da Silva, J. Yoneda, L. C. D. de Rezende, F. S. Emery, C. A. de Simone, E. N. da Silva Júnior* and L. F. Pedrosa*
Multi-conformational monomer and dimer steady-states in domains of few molecules: the consequences on the phosphorescence emission bands.
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G. H. R. Soares, G. A. M. Jardim, E. N. da Silva Júnior and L. A. Cury*
2018
Quinone-based fluorophores for imaging biological processes
G. G. Dias, A. King, F. de Moliner, M. Vendrell* and E. N. da Silva Júnior*
Featured in Front Cover
Highlighted in Themed collection 2018 Emerging Investigators.
Highlighted in Themed collection SBQ-RSC: Celebrating UK-Brazil collaborations.
Highlighted in Themed collection: Probes for in vitro and in vivo fluorescence imaging.
Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor
T. Rodrigues*, M. Werner, J. Roth, E. H. G. da Cruz, M. C. Marques, P. Akkapeddi, S. A. Lobo, A. Koeberle, F. Corzana, E. N. da Silva Júnior, O. Werz and G. J. L. Bernardes*
Featured in Inside Front Cover.
Highlighted in Chemistry World 2018, July 26, 2018 “Artificial intelligence seeks out new anticancer drugs”.
Highlighted in Themed collection: 2018 Chemical Science HOT Article Collection
Highlighted in Themed collection: Most impactful Chemical Biology articles of 2018
Weakly-coordinating N-oxide and carbonyl groups for metal catalyzed C–H activation: The case of A-ring functionalization
E. N. da Silva Júnior*, G. A. M. Jardim, R. S. Gomes, Y.-F. Liang and L. Ackermann*
Featured in Inside Front Cover.
Combination of Aryl Diselenides/Hydrogen Peroxide and Carbon Nanotube-Rhodium Nanohybrid for Naphthols Oxidation: An Efficient Route towards Trypanocidal Quinones
R. L. de Carvalho, G. A. M. Jardim, A. C. C. Santos, M. H. Araujo, W. X. C. Oliveira, A. C. S. Bombaça, R. F. S. Menna-Barreto, E. Gopi, E, Gravel, E. Doris* and E. N. da Silva Júnior*
Featured in Front Cover and Selected as HOT PAPER.
Cover Profile: Combination of Aryl Diselenides/Hydrogen Peroxide and Carbon Nanotube-Rhodium Nanohybrid for Naphthols Oxidation: An Efficient Route towards Trypanocidal Quinones
R. L. de Carvalho, G. A. M. Jardim, A. C. C. Santos, M. H. Araujo, W. X. C. Oliveira, A. C. S. Bombaça, R. F. S. Menna-Barreto, E. Gopi, E, Gravel, E. Doris* and E. N. da Silva Júnior*
Ruthenium-catalyzed C–H oxygenation of quinones by weak O-coordination for potent trypanocidal agents
G. G. Dias, T. Rogge, R. Kuniyil, C. Jacob, R. F. S. Menna-Barreto, E. N. da Silva Júnior* and L. Ackermann*
Quinonoid Compounds via Reactions of Lawsone and 2-Aminonaphthoquinone with α-Bromonitroalkenes and Nitroallylic Acetates: Structural Diversity by C-ring Modification and Cytotoxic Evaluation against Cancer Cells
T. V. Baiju, R. G. Almeida, S. T. Sivanandan, C. A. de Simone, L. M. Brito, B. C. Cavalcanti, C. Pessoa, I. N. N. Namboothiri* and E. N. da Silva Júnior*
Direct sequential C-H iodination/organoyl-thiolation for benzenoid A-ring modification of quinonoid deactivated systems: A new protocol for potent trypanocidal quinones
G. A. M. Jardim, W. X. C. Oliveira, R. P. de Freitas, R. F. S. Menna-Barreto, T. L. Silva, M. O. F. Goulart and E. N. da Silva Júnior*
Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions
G. A. M. Jardim, E. H. G. da Cruz, W. O. Valença, D. J. B. Lima, B. C. Cavalcanti, C. Pessoa, J. Rafique, A. L. Braga, C. Jacob* and E. N. da Silva Júnior*
Vibronic singlet and triplet steady-state interplay emissions in phenazine-based 1,2,3-triazole films
B. B. A. Costa, P. D. C. Souza, R. N. Gontijo, G. A. M. Jardim, R. L. Moreira, E. N. da Silva Júnior and L. A. Cury*
Multinuclear NMR spectroscopy, photophysical, electrochemical and DNA-binding properties of fluorinated 1,8-naphthyridine-based boron heterocycles
H. G. Bonacorso*, T. P. Calheiro, B. A. Iglesias, Carolina H. da Silveira, E. N. da Silva Júnior, A. Ketzer, F. Bublitz, N. Zanatta and M. A. P. Martins
A UBI 31-38 Peptide-coumarin Conjugate: Photophysical Features, Imaging Tracking and Synergism with Amphotericin B Against Cryptococcus
S. M. Z. M. D. Ferreira, H. C. Carneiro, R. B. Alves, A. C. S. Batista, E. N. da Silva Júnior, G. G. Dias, J. M. Resende, D. A. Santos, D. L. Oliveira, M. L. Rodrigues and R. P. Freitas*
Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplet
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F. de Moliner, A. King, G. G. Dias, G. F. de Lima, C A. de Simone, E N. da Silva Júnior* and M. Vendrell*
Action mechanism of naphthofuranquinones against fluconazole-resistant Candida tropicalis strains evidenced by proteomic analysis: The role of increased endogenous ROS
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J. B. A. Neto, C. R. da Silva, R. S. Campos, F. B. S. A. do Nascimento, L. S. Sampaio, A. R. da Silva, M. A. A. Josino, M. O. de Moraes, M. D. P. Lobo, F. B. M. B. Moreno, A. C. O. M. Moreira, R. A. Moreira, T. B. Grangeiro, E. N. da Silva Júnior, H. I. F. Magalhães, D. D. Rocha, B. C. Cavalcanti and H. V. Nobre Júnior*
2017
Indirect consequences of exciplex states on the phosphorescence lifetime of phenazine-based 1,2,3-triazole luminescent probe
B. B. A. Costa, G. A. M. Jardim, P. L. Santos, H. D. R. Calado, A. P. Monkman, F. B. Dias, E. N. da Silva Júnior and L. A. Cury*
Featured in Front Cover.
Highlighted in Themed collection SBQ-RSC: Celebrating UK-Brazil collaborations.
Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones
G. A. M. Jardim, T. L. Silva, M. O. F. Goulart, C. A. de Simone, J. M. C. Barbosa, K. Salomão, S. L. de Castro, J. F. Bower and E. N. da Silva Júnior*
Synthesis of Quinone-Based N-Sulfonyl-1,2,3-triazoles: Chemical Reactivity of Rh(II) Azavinyl Carbenes and Antitumor Activity
W. O. Valença, T. V. Baiju, F. G. Brito, M. H. Araujo, C. Pessoa, B. C. Cavalcanti, C. A. de Simone, C. Jacob, I. N. N. Namboothiri* and E. N. da Silva Júnior*
Cyclometalated ruthenium complexes from naturally occurring quinones: Studies on their photophysical features, computational details and trypanocidal activity
C. M. de Souza, R. C. Silva, P. O. Fernandes, J. D. de Souza Filho, H. A. Duarte, M. H. Araujo, C. A. de Simone, S. L. de Castro, R. F. S. Menna-Barreto, C. P. Demicheli and E. N. da Silva Júnior*
Featured in Front Cover.
​Redox Center Modification of Lapachones Toward the Syntheses of Nitrogenated Heterocycles as Selective Fluorescent Mitochondrial Imaging Probes
F. S. dos Santos, G. G. Dias, R. P. de Freitas, Lucas S. Santos, G. F. de Lima, H. A. Duarte, C. A. de Simone, L. M. S. L. Rezende, M. J. X. Vianna, J. R. Correa, B. A. D. Neto and E. N. da Silva Júnior*
Featured in Front Cover.
On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells
T. B. Gontijo, R. P. de Freitas, F. S. Emery, L. F. Pedrosa, J. B. Vieira Neto, B. C. Cavalcanti, C. Pessoa, A. King, F. de Moliner, M. Vendrell* and E. N. da Silva Júnior*
Encapsulation of nor-β-lapachone into poly(D,L)-lactide-co-glycolide (PLGA) microcapsules: full characterization, computational details and cytotoxic activity against human cancer cell lines
M. P. Costa, A. C. S. Feitosa, F. C. E. Oliveira, B. C. Cavalcanti, G. G. Dias, E. W. S. Caetano, F. A. M. Sales, V. N. Freire, S. Di Fiore, R. Fischer, L. O. Ladeira, E. N. da Silva Júnior* and C. Pessoa*
